Basic Information
ID: ALA4391657
Type: Toxicity
Description: Selectivity index, ratio of Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability after 48 hrs by SRB assay to Antiviral activity against Herpes simplex virus 2-333 infected in African green monkey Vero cells assessed as inhibition of viral replication after 48 hrs by naphthol blue-black staining-based plaque reduction assay
Format: BAO_0000219
Target: Unchecked(ALA612545)
Document: ALA4390653
Selectivity index, ratio of Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability after 48 hrs by SRB assay to Antiviral activity against Herpes simplex virus 2-333 infected in African green monkey Vero cells assessed as inhibition of viral replication after 48 hrs by naphthol blue-black staining-based plaque reduction assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4391657
Ratio CC50/IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 225.21 | -1.33 | -1.33 |
| 374.52 | 3.60 | 3.60 |
| 617.74 | 1.39 | 1.39 |
| 431.57 | 2.72 | 2.72 |
| 785.89 | 3.68 | 3.68 |
| 779.88 | -0.78 | -0.78 |
| 450.02 | 3.97 | 3.97 |
| 617.74 | 1.39 | 1.39 |
| 494.47 | 4.12 | 4.12 |
| 505.70 | 2.69 | 2.69 |
| 785.89 | 3.68 | 3.68 |
| 531.70 | 4.71 | 4.71 |
| 617.74 | 1.39 | 1.39 |
| 574.81 | 5.61 | 5.61 |
| 474.64 | 2.31 | 2.31 |
| 541.13 | 5.49 | 5.49 |
| 785.89 | 3.68 | 3.68 |
| 1074.14 |