Basic Information
ID: ALA4391728
Type: Binding
Description: Inhibition of human full length N-terminal GST-tagged PDE4B1 expressed in baculovirus infected Sf9 cells using cAMP as substrate incubated for 1 hr by fluorescence polarization assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Sf9
Target: Phosphodiesterase 4B(ALA275)
Document: ALA4390657
Inhibition of human full length N-terminal GST-tagged PDE4B1 expressed in baculovirus infected Sf9 cells using cAMP as substrate incubated for 1 hr by fluorescence polarization assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4391728
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 275.35 | 2.62 | 2.62 |
| 367.78 | 4.98 | 4.98 |
| 360.79 | 5.62 | 5.62 |
| 434.92 | 5.28 | 5.28 |
| 353.80 | 4.44 | 4.44 |
| 354.84 | 5.03 | 5.03 |
| 301.36 | 3.33 | 3.33 |
| 381.86 | 5.41 | 5.41 |
| 331.84 | 3.97 | 3.97 |
| 353.85 | 5.64 | 5.64 |
| 324.81 | 5.02 | 5.02 |
| 395.89 | 4.80 | 4.80 |
| 324.81 | 5.02 | 5.02 |
| 366.89 | 5.69 | 5.69 |
| 308.36 | 4.51 | 4.51 |
| 347.84 | 4.21 | 4.21 |
| 336.82 | 4.95 | 4.95 |
| 320.39 | 4.38 | 4.38 |
| 317.82 | 3.85 | 3.85 |
| 329.87 | 5.25 | 5.25 |
| 320.37 | 4.43 | 4.43 |
| 341.81 | 5.77 | 5.77 |
| 358.27 | 6.28 | 6.28 |