ID: ALA4391916
Type: Functional
Description: Antagonist activity at cloned human 5-HT1A receptor transfected in human HeLa cell membranes preincubated for 20 mins followed by [35S]GTPgammaS addition and measured after 30 mins by liquid scintillation counting
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HeLa
Target: Serotonin 1a (5-HT1a) receptor(ALA214)
Document: ALA4390666
Antagonist activity at cloned human 5-HT1A receptor transfected in human HeLa cell membranes preincubated for 20 mins followed by [35S]GTPgammaS addition and measured after 30 mins by liquid scintillation counting: 1
Bioactivity
Activity Types for Assay ALA4391916
pKb
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
422.57 | 3.83 | 3.83 |
444.58 | 4.18 | 4.18 |
343.42 | 2.82 | 2.82 |
419.52 | 4.02 | 4.02 |