Antagonist activity at cloned human 5-HT1A receptor transfected in human HeLa cell membranes preincubated for 20 mins followed by [35S]GTPgammaS addit...

Basic Information

ID: ALA4391916

Type: Functional

Description: Antagonist activity at cloned human 5-HT1A receptor transfected in human HeLa cell membranes preincubated for 20 mins followed by [35S]GTPgammaS addition and measured after 30 mins by liquid scintillation counting

Format: BAO_0000219

Organism: Homo sapiens

Cell type: HeLa

Target:  Serotonin 1a (5-HT1a) receptor(ALA214)

Document:  ALA4390666

Antagonist activity at cloned human 5-HT1A receptor transfected in human HeLa cell membranes preincubated for 20 mins followed by [35S]GTPgammaS addition and measured after 30 mins by liquid scintillation counting: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
422.573.833.83
444.584.184.18
343.422.822.82
419.524.024.02