Basic Information
ID: ALA4391917
Type: Functional
Description: Agonist activity at cloned human 5-HT1A receptor transfected in human HeLa cell membranes preincubated for 20 mins followed by [35S]GTPgammaS addition and measured after 30 mins by liquid scintillation counting relative to 8-OH-DPAT
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HeLa
Target: Serotonin 1a (5-HT1a) receptor(ALA214)
Document: ALA4390666
Agonist activity at cloned human 5-HT1A receptor transfected in human HeLa cell membranes preincubated for 20 mins followed by [35S]GTPgammaS addition and measured after 30 mins by liquid scintillation counting relative to 8-OH-DPAT: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4391917
Emax
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 419.52 | 4.02 | 4.02 |
| 389.50 | 4.01 | 4.01 |
| 389.50 | 4.01 | 4.01 |
| 343.42 | 2.82 | 2.82 |
| 444.58 | 4.18 | 4.18 |