Basic Information
ID: ALA4392088
Type: Binding
Description: Inhibition of Pks13 D1644G/N1640K double mutant thioesterase domain in Mycobacterium tuberculosis H37Rv assessed as reduction in bacterial growth by microplate alamar blue assay
Organism: Mycobacterium tuberculosis H37Rv
Activity Charts
Bioactivity
Activity Types for Assay ALA4392088
MIC=<90
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 401.44 | 2.37 | 2.37 |
| 137.14 | -0.31 | -0.31 |
| 204.31 | -0.29 | -0.29 |
| 484.50 | -7.29 | -7.29 |
| 585.61 | -8.42 | -8.42 |
| 822.95 | 4.34 | 4.34 |
| 1321.44 | ||
| 393.48 | 5.21 | 5.21 |
| 349.39 | 4.38 | 4.38 |
| 252.22 | 3.40 | 3.40 |
| 349.39 | 4.38 | 4.38 |
| 380.44 | 3.86 | 3.86 |
| 363.41 | 4.69 | 4.69 |
| 349.34 | 3.52 | 3.52 |
| 363.37 | 4.02 | 4.02 |
| 363.37 | 3.82 | 3.82 |
| 383.83 | 5.04 | 5.04 |
| 365.39 | 4.09 | 4.09 |
| 428.28 | 5.15 | 5.15 |
| 363.41 | 4.63 | 4.63 |
| 421.49 | 5.39 | 5.39 |
| 397.38 | 3.50 | 3.50 |
| 394.38 | 4.29 | 4.29 |
| 365.39 | 4.09 | 4.09 |
| 379.41 | 4.39 | 4.39 |
| 349.34 | 3.54 | 3.54 |
| 363.41 | 4.77 | 4.77 |
| 365.39 | 4.09 | 4.09 |
| 407.42 | 3.84 | 3.84 |
| 377.40 | 4.33 | 4.33 |
| 391.42 | 4.60 | 4.60 |
| 363.41 | 4.63 | 4.63 |
| 421.49 | 5.39 | 5.39 |
| 428.28 | 5.15 | 5.15 |
| 335.36 | 3.99 | 3.99 |
| 405.49 | 5.68 | 5.68 |
| 381.38 | 3.80 | 3.80 |
| 377.40 | 4.30 | 4.30 |
| 377.40 | 4.21 | 4.21 |
| 421.45 | 4.23 | 4.23 |
| 363.37 | 4.02 | 4.02 |
| 363.37 | 3.91 | 3.91 |
| 740.76 | 1.54 | 1.54 |