Basic Information
ID: ALA4392121
Type: Functional
Description: Agonist activity at recombinant human D1 receptor expressed in HEK29T cells assessed as induction of stimulatory G-protein-mediated cAMP accumulation measured after 15 mins by Glosensor-based FLIPR assay relative to dopamine
Format: BAO_0000219
Organism: Homo sapiens
Target: Dopamine D1 receptor(ALA2056)
Document: ALA4390674
Agonist activity at recombinant human D1 receptor expressed in HEK29T cells assessed as induction of stimulatory G-protein-mediated cAMP accumulation measured after 15 mins by Glosensor-based FLIPR assay relative to dopamine: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4392121
Emax
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 356.39 | 4.95 | 4.95 |
| 341.37 | 5.24 | 5.24 |
| 331.38 | 5.00 | 5.00 |
| 399.41 | 5.03 | 5.03 |
| 356.39 | 4.95 | 4.95 |
| 327.34 | 4.86 | 4.86 |
| 396.45 | 5.82 | 5.82 |
| 356.39 | 3.85 | 3.85 |
| 356.39 | 4.95 | 4.95 |
| 357.37 | 4.22 | 4.22 |
| 369.43 | 4.92 | 4.92 |
| 405.38 | 6.36 | 6.36 |
| 346.39 | 5.31 | 5.31 |
| 397.48 | 5.70 | 5.70 |
| 399.50 | 5.19 | 5.19 |
| 378.34 | 4.92 | 4.92 |
| 435.41 | 6.83 | 6.83 |
| 372.45 | 5.42 | 5.42 |
| 383.46 | 5.31 | 5.31 |
| 411.41 | 6.42 | 6.42 |
| 355.40 | 5.55 | 5.55 |
| 355.40 | 4.45 | 4.45 |
| 395.34 | 5.95 | 5.95 |
| 355.32 | 5.21 | 5.21 |
| 361.40 | 5.09 | 5.09 |
| 363.32 | 5.21 | 5.21 |
| 355.40 | 4.90 | 4.90 |
| 341.37 | 5.24 | 5.24 |
| 355.40 | 5.55 | 5.55 |
| 395.26 | 4.96 | 4.96 |
| 409.49 | 5.70 | 5.70 |
| 316.36 | 4.20 | 4.20 |
| 332.36 | 4.28 | 4.28 |
| 395.34 | 4.86 | 4.86 |
| 342.36 | 4.52 | 4.52 |
| 423.52 | 6.24 | 6.24 |
| 346.39 | 4.21 | 4.21 |
| 410.36 | 5.66 | 5.66 |
| 345.36 | 4.09 | 4.09 |
| 370.41 | 5.26 | 5.26 |
| 366.42 | 5.35 | 5.35 |
| 394.36 | 5.46 | 5.46 |
| 331.38 | 4.88 | 4.88 |
| 356.39 | 4.08 | 4.08 |