Assay Report Card

Basic Information

ID: ALA4392126

Type: Functional

Description: Bias factor, transduction co-efficient for agonist activity at recombinant human D1 receptor expressed in HEK29T cells assessed as induction of stimulatory G-protein-mediated cAMP accumulation to agonist activity at recombinant C-terminal RLuc8-fused human D1 receptor expressed in HEK29T cells co-expressing N-terminal Venus-tagged beta-arrestin2 assessed as increase in beta-arrestin2 recruitment

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
267.332.652.65
356.394.954.95
341.375.245.24
356.394.954.95
357.374.224.22
372.455.425.42
355.404.454.45
395.345.955.95
342.364.524.52
410.365.665.66
331.384.884.88