Basic Information
ID: ALA4392455
Type: ADME
Description: Inhibition of UGT1A1 in rat liver microsomes using beta-estradiol as substrate preincubated for 5 mins followed by substrate addition and measured after 40 mins by LC-MS/MS analysis
Organism: Rattus norvegicus
Tissue: Liver
Subcellular Fraction: Microsomes
Activity Charts
Bioactivity
Activity Types for Assay ALA4392455
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 704.87 | 4.21 | 4.21 |
| 852.05 | 5.33 | 5.33 |