Basic Information
ID: ALA4392492
Type: ADME
Description: Inhibition of human ACAT1
Format: BAO_0000357
Organism: Homo sapiens
Target: Acyl coenzyme A:cholesterol acyltransferase 1(ALA2782)
Document: ALA4390688
Inhibition of human ACAT1: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4392492
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 448.91 | 5.36 | 5.36 |
| 448.91 | 5.36 | 5.36 |
| 438.50 | 4.39 | 4.39 |
| 460.46 | 4.49 | 4.49 |
| 355.32 | 5.02 | 5.02 |
| 428.49 | 5.10 | 5.10 |
| 437.47 | 5.06 | 5.06 |
| 447.93 | 5.03 | 5.03 |
| 459.55 | 4.52 | 4.52 |
| 496.49 | 6.12 | 6.12 |
| 459.51 | 4.50 | 4.50 |
| 462.94 | 5.75 | 5.75 |
| 419.87 | 4.62 | 4.62 |
| 436.48 | 5.67 | 5.67 |
| 364.33 | 5.18 | 5.18 |
| 464.47 | 5.38 | 5.38 |
| 434.88 | 4.97 | 4.97 |
| 420.86 | 4.58 | 4.58 |
| 452.53 | 4.78 | 4.78 |
| 447.93 | 5.40 | 5.40 |
| 469.97 | 4.69 | 4.69 |
| 470.52 | 4.92 | 4.92 |
| 442.86 | 5.83 | 5.83 |
| 420.86 | 4.58 | 4.58 |
| 434.54 | 4.64 | 4.64 |
| 363.34 | 5.79 | 5.79 |
| 468.99 | 5.30 | 5.30 |
| 447.93 | 5.03 | 5.03 |
| 446.48 | 5.24 | 5.24 |
| 447.93 | 5.03 | 5.03 |
| 465.55 | 4.05 | 4.05 |
| 339.32 | 5.31 | 5.31 |
| 436.86 | 3.82 | 3.82 |
| 420.86 | 4.44 | 4.44 |
| 497.48 | 5.51 | 5.51 |
| 503.53 | 5.06 | 5.06 |
| 444.96 | 7.30 | 7.30 |
| 419.87 | 4.62 | 4.62 |
| 338.33 | 5.92 | 5.92 |
| 443.51 | 4.80 | 4.80 |
| 464.47 | 5.38 | 5.38 |
| 447.93 | 5.40 | 5.40 |
| 478.51 | 7.66 | 7.66 |
| 453.50 | 4.97 | 4.97 |
| 475.98 | 5.67 | 5.67 |
| 449.56 | 4.35 | 4.35 |
| 502.54 | 5.66 | 5.66 |
| 424.43 | 5.15 | 5.15 |
| 354.33 | 5.62 | 5.62 |
| 455.91 | 5.65 | 5.65 |
| 422.87 | 4.83 | 4.83 |
| 463.93 | 5.15 | 5.15 |
| 470.52 | 4.92 | 4.92 |