ID: ALA4392552
Type: Binding
Description: Inhibition of recombinant human N-terminal FLAG-tagged PRMT5 (1 to 637 residue) /full length human N-terminal His tagged MEP50 expressed in baculovirus infected Sf9 insect cells assessed as reduction in methyl transfer from [3H]-SAM to biotinylated histone H4 peptide H-SGRGKGGKGLGKGGAKRHRKVLRDK-Biotin measured after 2 hrs by liquid scintillation counting
Organism: Homo sapiens
Cell type: Sf9
Bioactivity
Activity Types for Assay ALA4392552
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
342.36 | 0.37 | 0.37 |
376.80 | 1.02 | 1.02 |