Basic Information
ID: ALA4392553
Type: Binding
Description: Inhibition of full length N-terminal FLAG-tagged PRMT5 (unknown origin)/MEP50 (unknown origin) expressed in baculovirus infected Sf21 insect cells using H4(1-21) peptide SGRGKGGKGLGKGGAKRHRKV as substrate measured after 25 minutes in the presence of [3H]SAM by liquid scintillation counting
Organism: Homo sapiens
Cell type: Sf21
Activity Charts
Bioactivity
Activity Types for Assay ALA4392553
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 396.33 | 0.78 | 0.78 |
| 379.32 | 0.04 | 0.04 |
| 378.34 | 0.64 | 0.64 |
| 376.36 | 1.34 | 1.34 |
| 377.35 | 1.37 | 1.37 |
| 376.80 | 1.02 | 1.02 |