Basic Information
ID: ALA4392600
Type: ADME
Description: Prodrug activation in pH 7.4 PBS buffer assessed as 3.3 ug/mL NADPH-cytochrome P450 reductase (unknown origin) mediated FdUrd formation at 0.62 mM in the presence of beta-NADPH measured after 2 hrs under hypoxic condition by reverse phase HPLC relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4392600
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 463.42 | -0.61 | -0.61 |
| 462.43 | -1.03 | -1.03 |