ID: ALA4392605
Type: ADME
Description: Prodrug conversion in pH 7.4 PBS buffer assessed as NADPH-cytochrome P450 reductase (unknown origin) mediated FdUrd release by measuring Km at 0.62 mM in the presence of beta-NADPH measured after 2 hrs under hypoxic condition by Lineweaver-Burk plot analysis
Organism: Homo sapiens
Bioactivity
Activity Types for Assay ALA4392605
Km
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
463.42 | -0.61 | -0.61 |