Assay Report Card

Basic Information

ID: ALA4392605

Type: ADME

Description: Prodrug conversion in pH 7.4 PBS buffer assessed as NADPH-cytochrome P450 reductase (unknown origin) mediated FdUrd release by measuring Km at 0.62 mM in the presence of beta-NADPH measured after 2 hrs under hypoxic condition by Lineweaver-Burk plot analysis

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
463.42-0.61-0.61