Basic Information
ID: ALA4392788
Type: Binding
Description: Inhibition of recombinant human Pin1 (Met1 to Glu163 residues) expressed in Escherichia coli using Suc-Ala-Glu-cis-Pro-Phe-4-nitroanilide as substrate preincubated for 30 mins followed by substrate addition and measured for 90 secs by protease-coupled assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4392788
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 174.16 | 1.33 | 1.33 |
| 337.38 | 3.08 | 3.08 |
| 561.66 | 6.44 | 6.44 |
| 415.45 | 4.44 | 4.44 |
| 553.56 | 5.91 | 5.91 |
| 454.31 | 5.74 | 5.74 |
| 399.45 | 4.74 | 4.74 |
| 478.50 | 6.19 | 6.19 |
| 464.52 | 6.66 | 6.66 |
| 442.52 | 5.69 | 5.69 |
| 351.41 | 3.39 | 3.39 |
| 436.47 | 5.55 | 5.55 |
| 351.41 | 3.39 | 3.39 |
| 430.42 | 4.34 | 4.34 |
| 499.59 | 5.02 | 5.02 |
| 448.91 | 5.67 | 5.67 |
| 445.48 | 4.45 | 4.45 |
| 399.45 | 4.74 | 4.74 |
| 422.48 | 6.02 | 6.02 |
| 453.42 | 5.45 | 5.45 |
| 489.58 | 6.02 | 6.02 |
| 511.58 | 7.31 | 7.31 |
| 428.53 | 6.17 | 6.17 |
| 434.92 | 6.14 | 6.14 |