Basic Information
ID: ALA4392932
Type: Binding
Description: Selectivity index, ratio of IC50 for inhibition of native soluble pig heart MDH to IC50 for inhibition of Escherichia coli GroEL expressed in Escherichia coli DH5alpha/Escherichia coli GroES expressed in Escherichia coli BL21 (DE3) assessed as reduction in GroEL/GroES-mediated denatured rhodanese refolding by measuring rhodanese enzyme activity after 45 mins by Fe(SCN)3 dye based spectrometric analysis
Activity Charts
Bioactivity
Activity Types for Assay ALA4392932
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 303.14 | 3.61 | 3.61 |
| 224.26 | 3.29 | 3.29 |
| 224.26 | 3.29 | 3.29 |
| 853.92 | 3.74 | 3.74 |
| 406.91 | 6.61 | 6.61 |
| 172.18 | 2.01 | 2.01 |
| 368.39 | 3.37 | 3.37 |
| 269.13 | 4.00 | 4.00 |
| 238.29 | 3.59 | 3.59 |
| 458.38 | 2.23 | 2.23 |
| 256.21 | 1.58 | 1.58 |
| 407.99 | 4.46 | 4.46 |
| 384.65 | 7.62 | 7.62 |
| 416.56 | 4.85 | 4.85 |
| 875.11 | 5.60 | 5.60 |
| 412.53 | 6.68 | 6.68 |
| 220.36 | 4.69 | 4.69 |
| 448.09 | 6.07 | 6.07 |
| 424.09 | 5.46 | 5.46 |
| 376.58 | 5.51 | 5.51 |
| 396.66 | 7.64 | 7.64 |
| 960.82 | 6.67 | 6.67 |
| 340.29 | 4.19 | 4.19 |
| 562.67 | 7.50 | 7.50 |
| 300.27 | 1.33 | 1.33 |
| 578.61 | 6.38 | 6.38 |
| 873.09 | 5.38 | 5.38 |
| 914.14 | 5.52 | 5.52 |
| 358.01 | 6.46 | 6.46 |