Basic Information
ID: ALA4392933
Type: Binding
Description: Inhibition of human N-terminal octa-His-tagged HSP60 expressed in Escherichia coli Rosetta(DE3) pLysS/human HSP10 expressed in Escherichia coli Rosetta(DE3) assessed as reduction in HSP60/HSP10-mediated denatured MDH refolding by measuring MDH enzyme activity using sodium mesoxalate as substrate after 40 to 60 mins by malachite green dye based spectrometric analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4392933
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 300.44 | 5.60 | 5.60 |
| 303.14 | 3.61 | 3.61 |
| 224.26 | 3.29 | 3.29 |
| 224.26 | 3.29 | 3.29 |
| 853.92 | 3.74 | 3.74 |
| 406.91 | 6.61 | 6.61 |
| 663.08 | 7.12 | 7.12 |
| 259.35 | 2.78 | 2.78 |
| 422.35 | 2.45 | 2.45 |
| 733.94 | 1.79 | 1.79 |
| 242.27 | 2.75 | 2.75 |
| 304.47 | 6.22 | 6.22 |
| 172.18 | 2.01 | 2.01 |
| 368.39 | 3.37 | 3.37 |
| 153.14 | 0.67 | 0.67 |
| 239.31 | 1.31 | 1.31 |
| 302.24 | 1.99 | 1.99 |
| 269.13 | 4.00 | 4.00 |
| 356.06 | 5.86 | 5.86 |
| 238.29 | 3.59 | 3.59 |
| 394.32 | 4.13 | 4.13 |
| 188.18 | 1.72 | 1.72 |
| 458.38 | 2.23 | 2.23 |
| 357.45 | 1.71 | 1.71 |
| 256.21 | 1.58 | 1.58 |
| 407.99 | 4.46 | 4.46 |
| 440.46 | 4.03 | 4.03 |
| 384.65 | 7.62 | 7.62 |
| 416.56 | 4.85 | 4.85 |
| 875.11 | 5.60 | 5.60 |
| 200.24 | 2.24 | 2.24 |
| 412.53 | 6.68 | 6.68 |
| 220.36 | 4.69 | 4.69 |
| 414.54 | 4.62 | 4.62 |
| 448.09 | 6.07 | 6.07 |
| 424.09 | 5.46 | 5.46 |
| 376.58 | 5.51 | 5.51 |
| 318.24 | 1.69 | 1.69 |
| 376.37 | -1.72 | -1.72 |
| 396.66 | 7.64 | 7.64 |
| 1701.21 | ||
| 373.91 | 2.50 | 2.50 |
| 960.82 | 6.67 | 6.67 |
| 340.29 | 4.19 | 4.19 |
| 419.35 | 3.36 | 3.36 |
| 562.67 | 7.50 | 7.50 |
| 300.27 | 1.33 | 1.33 |
| 578.61 | 6.38 | 6.38 |
| 873.09 | 5.38 | 5.38 |
| 914.14 | 5.52 | 5.52 |
| 358.01 | 6.46 | 6.46 |
| 879.86 | 6.08 | 6.08 |
| 1664.92 | ||
| 1297.30 | ||
| 514.36 | -1.61 | -1.61 |
| 996.85 | 8.74 | 8.74 |
| 405.40 | 3.58 | 3.58 |