Basic Information
ID: ALA4392938
Type: Binding
Description: Inhibition of Escherichia coli GroEL expressed in Escherichia coliDH5alpha/Escherichia coli GroES expressed in Escherichia coli BL21 (DE3) assessed as reduction in GroEL/GroES-mediated denatured soluble pig heart MDH refolding by measuring MDH enzyme activity using sodium mesoxalate as substrate after 20 to 40 mins by malachite green dye based spectrometric analysis relative to untreated control
Organism: Escherichia coli
Activity Charts
Bioactivity
Activity Types for Assay ALA4392938
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 168.15 | 1.22 | 1.22 |
| 300.44 | 5.60 | 5.60 |
| 303.14 | 3.61 | 3.61 |
| 224.26 | 3.29 | 3.29 |
| 224.26 | 3.29 | 3.29 |
| 853.92 | 3.74 | 3.74 |
| 406.91 | 6.61 | 6.61 |
| 663.08 | 7.12 | 7.12 |
| 259.35 | 2.78 | 2.78 |
| 348.49 | 6.29 | 6.29 |
| 422.35 | 2.45 | 2.45 |
| 733.94 | 1.79 | 1.79 |
| 242.27 | 2.75 | 2.75 |
| 242.27 | 3.23 | 3.23 |
| 304.47 | 6.22 | 6.22 |
| 172.18 | 2.01 | 2.01 |
| 407.58 | 5.68 | 5.68 |
| 368.39 | 3.37 | 3.37 |
| 153.14 | 0.67 | 0.67 |
| 239.31 | 1.31 | 1.31 |
| 472.09 | 8.01 | 8.01 |
| 302.24 | 1.99 | 1.99 |
| 269.13 | 4.00 | 4.00 |
| 356.06 | 5.86 | 5.86 |
| 238.29 | 3.59 | 3.59 |
| 394.32 | 4.13 | 4.13 |
| 516.55 | 5.40 | 5.40 |
| 442.38 | 2.53 | 2.53 |
| 368.30 | 2.01 | 2.01 |
| 188.18 | 1.72 | 1.72 |
| 174.16 | 1.33 | 1.33 |
| 458.38 | 2.23 | 2.23 |
| 357.45 | 1.71 | 1.71 |
| 518.56 | 6.38 | 6.38 |
| 158.16 | 1.62 | 1.62 |
| 149.22 | 2.29 | 2.29 |
| 450.62 | 6.70 | 6.70 |
| 256.21 | 1.58 | 1.58 |
| 154.12 | -0.30 | -0.30 |
| 351.86 | 2.69 | 2.69 |
| 331.80 | 3.33 | 3.33 |
| 407.99 | 4.46 | 4.46 |
| 197.19 | 0.05 | 0.05 |
| 440.46 | 4.03 | 4.03 |
| 215.17 | 1.73 | 1.73 |
| 384.65 | 7.62 | 7.62 |
| 416.56 | 4.85 | 4.85 |
| 240.26 | 2.99 | 2.99 |
| 188.18 | 1.60 | 1.60 |
| 410.47 | 5.09 | 5.09 |
| 213.19 | -0.24 | -0.24 |
| 875.11 | 5.60 | 5.60 |
| 240.26 | 2.99 | 2.99 |
| 200.24 | 2.24 | 2.24 |
| 412.53 | 6.68 | 6.68 |
| 220.36 | 4.69 | 4.69 |
| 564.50 | 2.21 | 2.21 |
| 868.71 | 4.18 | 4.18 |
| 270.28 | 3.00 | 3.00 |
| 294.35 | 4.25 | 4.25 |
| 245.88 | 2.52 | 2.52 |
| 414.54 | 4.62 | 4.62 |
| 448.09 | 6.07 | 6.07 |
| 424.09 | 5.46 | 5.46 |
| 248.32 | 2.76 | 2.76 |
| 433.61 | 6.23 | 6.23 |
| 278.31 | 3.29 | 3.29 |
| 376.58 | 5.51 | 5.51 |
| 174.15 | 1.51 | 1.51 |
| 417.63 | 6.79 | 6.79 |
| 318.24 | 1.69 | 1.69 |
| 376.37 | -1.72 | -1.72 |
| 396.66 | 7.64 | 7.64 |
| 218.21 | 1.57 | 1.57 |
| 598.70 | 6.11 | 6.11 |
| 482.57 | 4.56 | 4.56 |
| 205.64 | 0.30 | 0.30 |
| 1701.21 | ||
| 516.58 | 2.55 | 2.55 |
| 250.25 | 1.72 | 1.72 |
| 466.57 | 5.35 | 5.35 |
| 426.73 | 8.48 | 8.48 |
| 524.87 | 11.54 | 11.54 |
| 419.15 | 4.02 | 4.02 |
| 367.92 | 5.32 | 5.32 |
| 248.19 | 1.01 | 1.01 |
| 456.49 | 5.53 | 5.53 |
| 628.76 | 7.24 | 7.24 |
| 373.91 | 2.50 | 2.50 |
| 330.34 | 3.02 | 3.02 |
| 284.27 | 1.62 | 1.62 |
| 452.64 | 6.64 | 6.64 |
| 642.79 | 7.33 | 7.33 |
| 142.07 | -2.08 | -2.08 |
| 1109.32 | ||
| 960.82 | 6.67 | 6.67 |
| 340.29 | 4.19 | 4.19 |
| 591.72 | 8.05 | 8.05 |
| 182.22 | -0.25 | -0.25 |
| 687.71 | 10.29 | 10.29 |
| 527.57 | 0.47 | 0.47 |
| 250.25 | -1.32 | -1.32 |
| 168.15 | 1.22 | 1.22 |
| 466.48 | 0.42 | 0.42 |
| 419.35 | 3.36 | 3.36 |
| 336.56 | 7.30 | 7.30 |
| 562.67 | 7.50 | 7.50 |
| 254.29 | 3.18 | 3.18 |
| 300.27 | 1.33 | 1.33 |
| 240.99 | 2.00 | 2.00 |
| 393.28 | 6.20 | 6.20 |
| 570.46 | 3.01 | 3.01 |
| 646.78 | 7.52 | 7.52 |
| 396.40 | 3.49 | 3.49 |
| 312.32 | 3.07 | 3.07 |
| 578.61 | 6.38 | 6.38 |
| 262.22 | 1.10 | 1.10 |
| 222.24 | 2.16 | 2.16 |
| 873.09 | 5.38 | 5.38 |
| 280.45 | 5.72 | 5.72 |
| 914.14 | 5.52 | 5.52 |
| 520.95 | 5.01 | 5.01 |
| 358.01 | 6.46 | 6.46 |
| 879.86 | 6.08 | 6.08 |
| 422.52 | 4.89 | 4.89 |
| 1664.92 | ||
| 862.75 | -1.10 | -1.10 |
| 716.60 | 3.19 | 3.19 |
| 914.78 | 3.56 | 3.56 |
| 1297.30 | ||
| 316.44 | 4.30 | 4.30 |
| 422.52 | 4.80 | 4.80 |
| 343.55 | ||
| 514.36 | -1.61 | -1.61 |
| 536.71 | 7.08 | 7.08 |
| 418.49 | 5.32 | 5.32 |
| 996.85 | 8.74 | 8.74 |
| 414.37 | 1.51 | 1.51 |
| 887.12 | 5.89 | 5.89 |
| 264.19 | 0.72 | 0.72 |
| 480.56 | 4.43 | 4.43 |
| 656.82 | 7.63 | 7.63 |
| 405.40 | 3.58 | 3.58 |
| 873.09 | 5.23 | 5.23 |
| 670.80 | 7.46 | 7.46 |
| 440.54 | 3.99 | 3.99 |
| 298.38 | 3.39 | 3.39 |
| 630.78 | 7.03 | 7.03 |