Basic Information
ID: ALA4392939
Type: Binding
Description: Inhibition of Escherichia coli GroEL expressed in Escherichia coli DH5alpha/Escherichia coli GroES expressed in Escherichia coli BL21 (DE3) assessed as reduction in GroEL/GroES-mediated denatured rhodanese refolding by measuring rhodanese enzyme activity after 45 mins by Fe(SCN)3 dye based spectrometric analysis relative to untreated control
Organism: Escherichia coli
Activity Charts
Bioactivity
Activity Types for Assay ALA4392939
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 168.15 | 1.22 | 1.22 |
| 300.44 | 5.60 | 5.60 |
| 303.14 | 3.61 | 3.61 |
| 224.26 | 3.29 | 3.29 |
| 224.26 | 3.29 | 3.29 |
| 853.92 | 3.74 | 3.74 |
| 406.91 | 6.61 | 6.61 |
| 663.08 | 7.12 | 7.12 |
| 259.35 | 2.78 | 2.78 |
| 348.49 | 6.29 | 6.29 |
| 422.35 | 2.45 | 2.45 |
| 733.94 | 1.79 | 1.79 |
| 242.27 | 2.75 | 2.75 |
| 242.27 | 3.23 | 3.23 |
| 304.47 | 6.22 | 6.22 |
| 172.18 | 2.01 | 2.01 |
| 407.58 | 5.68 | 5.68 |
| 368.39 | 3.37 | 3.37 |
| 153.14 | 0.67 | 0.67 |
| 239.31 | 1.31 | 1.31 |
| 472.09 | 8.01 | 8.01 |
| 302.24 | 1.99 | 1.99 |
| 269.13 | 4.00 | 4.00 |
| 356.06 | 5.86 | 5.86 |
| 238.29 | 3.59 | 3.59 |
| 394.32 | 4.13 | 4.13 |
| 516.55 | 5.40 | 5.40 |
| 442.38 | 2.53 | 2.53 |
| 368.30 | 2.01 | 2.01 |
| 188.18 | 1.72 | 1.72 |
| 174.16 | 1.33 | 1.33 |
| 458.38 | 2.23 | 2.23 |
| 357.45 | 1.71 | 1.71 |
| 518.56 | 6.38 | 6.38 |
| 158.16 | 1.62 | 1.62 |
| 149.22 | 2.29 | 2.29 |
| 450.62 | 6.70 | 6.70 |
| 256.21 | 1.58 | 1.58 |
| 154.12 | -0.30 | -0.30 |
| 351.86 | 2.69 | 2.69 |
| 331.80 | 3.33 | 3.33 |
| 407.99 | 4.46 | 4.46 |
| 197.19 | 0.05 | 0.05 |
| 440.46 | 4.03 | 4.03 |
| 215.17 | 1.73 | 1.73 |
| 384.65 | 7.62 | 7.62 |
| 416.56 | 4.85 | 4.85 |
| 240.26 | 2.99 | 2.99 |
| 188.18 | 1.60 | 1.60 |
| 410.47 | 5.09 | 5.09 |
| 213.19 | -0.24 | -0.24 |
| 875.11 | 5.60 | 5.60 |
| 240.26 | 2.99 | 2.99 |
| 200.24 | 2.24 | 2.24 |
| 412.53 | 6.68 | 6.68 |
| 220.36 | 4.69 | 4.69 |
| 564.50 | 2.21 | 2.21 |
| 868.71 | 4.18 | 4.18 |
| 270.28 | 3.00 | 3.00 |
| 294.35 | 4.25 | 4.25 |
| 245.88 | 2.52 | 2.52 |
| 414.54 | 4.62 | 4.62 |
| 448.09 | 6.07 | 6.07 |
| 424.09 | 5.46 | 5.46 |
| 248.32 | 2.76 | 2.76 |
| 433.61 | 6.23 | 6.23 |
| 278.31 | 3.29 | 3.29 |
| 376.58 | 5.51 | 5.51 |
| 174.15 | 1.51 | 1.51 |
| 417.63 | 6.79 | 6.79 |
| 318.24 | 1.69 | 1.69 |
| 376.37 | -1.72 | -1.72 |
| 396.66 | 7.64 | 7.64 |
| 218.21 | 1.57 | 1.57 |
| 598.70 | 6.11 | 6.11 |
| 482.57 | 4.56 | 4.56 |
| 205.64 | 0.30 | 0.30 |
| 1701.21 | ||
| 516.58 | 2.55 | 2.55 |
| 250.25 | 1.72 | 1.72 |
| 466.57 | 5.35 | 5.35 |
| 426.73 | 8.48 | 8.48 |
| 524.87 | 11.54 | 11.54 |
| 419.15 | 4.02 | 4.02 |
| 367.92 | 5.32 | 5.32 |
| 248.19 | 1.01 | 1.01 |
| 456.49 | 5.53 | 5.53 |
| 628.76 | 7.24 | 7.24 |
| 373.91 | 2.50 | 2.50 |
| 330.34 | 3.02 | 3.02 |
| 284.27 | 1.62 | 1.62 |
| 452.64 | 6.64 | 6.64 |
| 642.79 | 7.33 | 7.33 |
| 142.07 | -2.08 | -2.08 |
| 1109.32 | ||
| 960.82 | 6.67 | 6.67 |
| 340.29 | 4.19 | 4.19 |
| 591.72 | 8.05 | 8.05 |
| 182.22 | -0.25 | -0.25 |
| 687.71 | 10.29 | 10.29 |
| 527.57 | 0.47 | 0.47 |
| 250.25 | -1.32 | -1.32 |
| 168.15 | 1.22 | 1.22 |
| 466.48 | 0.42 | 0.42 |
| 419.35 | 3.36 | 3.36 |
| 336.56 | 7.30 | 7.30 |
| 562.67 | 7.50 | 7.50 |
| 254.29 | 3.18 | 3.18 |
| 300.27 | 1.33 | 1.33 |
| 240.99 | 2.00 | 2.00 |
| 393.28 | 6.20 | 6.20 |
| 570.46 | 3.01 | 3.01 |
| 646.78 | 7.52 | 7.52 |
| 396.40 | 3.49 | 3.49 |
| 312.32 | 3.07 | 3.07 |
| 578.61 | 6.38 | 6.38 |
| 262.22 | 1.10 | 1.10 |
| 222.24 | 2.16 | 2.16 |
| 873.09 | 5.38 | 5.38 |
| 280.45 | 5.72 | 5.72 |
| 914.14 | 5.52 | 5.52 |
| 520.95 | 5.01 | 5.01 |
| 358.01 | 6.46 | 6.46 |
| 879.86 | 6.08 | 6.08 |
| 422.52 | 4.89 | 4.89 |
| 1664.92 | ||
| 862.75 | -1.10 | -1.10 |
| 716.60 | 3.19 | 3.19 |
| 914.78 | 3.56 | 3.56 |
| 1297.30 | ||
| 316.44 | 4.30 | 4.30 |
| 422.52 | 4.80 | 4.80 |
| 343.55 | ||
| 514.36 | -1.61 | -1.61 |
| 536.71 | 7.08 | 7.08 |
| 418.49 | 5.32 | 5.32 |
| 996.85 | 8.74 | 8.74 |
| 414.37 | 1.51 | 1.51 |
| 887.12 | 5.89 | 5.89 |
| 264.19 | 0.72 | 0.72 |
| 480.56 | 4.43 | 4.43 |
| 656.82 | 7.63 | 7.63 |
| 405.40 | 3.58 | 3.58 |
| 873.09 | 5.23 | 5.23 |
| 670.80 | 7.46 | 7.46 |
| 440.54 | 3.99 | 3.99 |
| 298.38 | 3.39 | 3.39 |
| 630.78 | 7.03 | 7.03 |