ID: ALA4393073
Type: Functional
Description: Negative allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galpha15 assessed as minimum L-AP4 response by measuring reduction in calcium mobilization incubated for 142 secs prior to glutamate addition for 120 secs followed by L-AP4 addition and measured after 40 secs by Fluo-4 AM dye based fluorescence assay relative to L-AP4 alone
Organism: Rattus norvegicus
Bioactivity
Activity Types for Assay ALA4393073
Activity
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
432.36 | 4.51 | 4.51 |
432.36 | 4.51 | 4.51 |
473.41 | 4.68 | 4.68 |
433.35 | 3.90 | 3.90 |
431.37 | 4.24 | 4.24 |
449.41 | 5.44 | 5.44 |
434.33 | 3.30 | 3.30 |
473.41 | 4.82 | 4.82 |
451.34 | 4.04 | 4.04 |
433.35 | 3.90 | 3.90 |
432.36 | 4.71 | 4.71 |
446.39 | 4.72 | 4.72 |
432.36 | 4.51 | 4.51 |
432.36 | 3.43 | 3.43 |
449.41 | 4.37 | 4.37 |
449.43 | 5.31 | 5.31 |
451.40 | 4.16 | 4.16 |
432.36 | 4.51 | 4.51 |
444.37 | 4.78 | 4.78 |
404.31 | 3.29 | 3.29 |
433.35 | 3.90 | 3.90 |
443.38 | 5.38 | 5.38 |