Basic Information
ID: ALA4393309
Type: Binding
Description: Inhibition of MERS-CoV papain-like protease using Z-Arg-Leu-Arg-Gly-Gly-AMC as substrate preincubated for 5 mins followed by substrate addition and measured for 10 mins by fluorescence assay
Organism: Middle East respiratory syndrome-related coronavirus
Activity Charts
Bioactivity
Activity Types for Assay ALA4393309
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 483.53 | 3.41 | 3.41 |
| 155.11 | 1.01 | 1.01 |
| 207.23 | 1.00 | 1.00 |
| 138.12 | 0.91 | 0.91 |
| 199.55 | 1.78 | 1.78 |
| 278.33 | 1.41 | 1.41 |
| 139.11 | 0.57 | 0.57 |
| 269.28 | -1.08 | -1.08 |
| 279.32 | 0.68 | 0.68 |
| 321.36 | 1.06 | 1.06 |
| 268.38 | 2.22 | 2.22 |