Assay Report Card

Basic Information

ID: ALA4393317

Type: Binding

Description: Reversible inhibition of MERS-CoV papain-like protease assessed as recovery of enzyme activity at 125 times IC50 using Z-Arg-Leu-Arg-Gly-Gly-AMC as substrate incubated for 1 hr followed by 2-fold dilution and measured by fluorescence assay

Organism: Middle East respiratory syndrome-related coronavirus

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
279.320.680.68