Basic Information
ID: ALA4393356
Type: ADME
Description: Inhibition of human MMP9 using (7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(3-(2,4-dinitrophenyl)-L-2,3-diamino-propionyl)Ala-Arg-NH2 as substrate preincubated for 30 mins followed by substrate addition and measured by fluorescence assay
Format: BAO_0000357
Organism: Homo sapiens
Target: Matrix metalloproteinase 9(ALA321)
Document: ALA4392848
Inhibition of human MMP9 using (7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(3-(2,4-dinitrophenyl)-L-2,3-diamino-propionyl)Ala-Arg-NH2 as substrate preincubated for 30 mins followed by substrate addition and measured by fluorescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4393356
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 393.47 | 1.81 | 1.81 |
| 420.51 | 2.90 | 2.90 |
| 449.51 | 1.00 | 1.00 |
| 481.57 | 0.69 | 0.69 |
| 433.51 | 2.03 | 2.03 |
| 465.51 | -0.03 | -0.03 |
| 419.53 | 2.39 | 2.39 |
| 435.52 | 1.36 | 1.36 |
| 420.51 | 2.90 | 2.90 |
| 465.51 | -0.03 | -0.03 |
| 505.57 | 1.77 | 1.77 |
| 449.51 | 1.00 | 1.00 |
| 454.50 | 2.69 | 2.69 |
| 433.51 | 2.03 | 2.03 |