Basic Information
ID: ALA4393448
Type: Binding
Description: Inhibition of hypoxia-induced HIF1alpha transcriptional activity in human Hep3B cells after 24 hrs in hypoxic condition by HRE-dependent dual luciferase reporter gene assay
Format: BAO_0000219
Organism: Homo sapiens
Target: Hypoxia-inducible factor 1 alpha(ALA4261)
Document: ALA4392861
Inhibition of hypoxia-induced HIF1alpha transcriptional activity in human Hep3B cells after 24 hrs in hypoxic condition by HRE-dependent dual luciferase reporter gene assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4393448
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 456.71 | 7.09 | 7.09 |
| 628.90 | 7.90 | 7.90 |
| 642.93 | 8.29 | 8.29 |
| 633.32 | 8.91 | 8.91 |
| 641.90 | 8.05 | 8.05 |
| 657.94 | 8.23 | 8.23 |
| 619.77 | 7.27 | 7.27 |
| 672.96 | 8.30 | 8.30 |
| 655.93 | 8.44 | 8.44 |
| 565.80 | 6.38 | 6.38 |
| 643.92 | 7.84 | 7.84 |
| 657.94 | 8.23 | 8.23 |
| 657.94 | 8.23 | 8.23 |
| 672.91 | 7.63 | 7.63 |
| 523.77 | 6.16 | 6.16 |
| 521.75 | 6.36 | 6.36 |
| 579.83 | 6.77 | 6.77 |
| 658.93 | 7.91 | 7.91 |
| 643.92 | 7.84 | 7.84 |
| 655.93 | 8.44 | 8.44 |
| 565.80 | 6.73 | 6.73 |
| 641.90 | 8.05 | 8.05 |
| 686.94 | 8.02 | 8.02 |
| 677.37 | 8.95 | 8.95 |
| 611.88 | 8.26 | 8.26 |
| 567.82 | 6.17 | 6.17 |
| 627.87 | 8.02 | 8.02 |
| 643.92 | 7.84 | 7.84 |
| 629.89 | 7.55 | 7.55 |
| 593.86 | 7.51 | 7.51 |
| 641.90 | 8.05 | 8.05 |
| 655.93 | 8.44 | 8.44 |
| 581.85 | 6.56 | 6.56 |
| 663.35 | 8.56 | 8.56 |