Basic Information
ID: ALA4393790
Type: Binding
Description: Inhibition of FLAP in human whole blood assessed as reduction in calcium ionophore-stimulated LTB4 production preincubated for 4 hrs followed by calcium ionophore stimulation and measured after 20 mins by EIA
Organism: Homo sapiens
Tissue: Blood
Activity Charts
Bioactivity
Activity Types for Assay ALA4393790
fIC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 434.50 | 2.69 | 2.69 |
| 434.50 | 2.85 | 2.85 |
| 434.50 | 2.85 | 2.85 |
| 470.56 | 2.39 | 2.39 |
| 450.50 | 2.87 | 2.87 |
| 434.50 | 3.14 | 3.14 |
| 405.50 | 4.05 | 4.05 |
| 446.51 | 2.95 | 2.95 |
| 448.53 | 3.15 | 3.15 |
| 448.53 | 3.33 | 3.33 |
| 506.61 | 4.21 | 4.21 |
| 435.48 | 3.44 | 3.44 |