Basic Information
ID: ALA4394179
Type: Binding
Description: Inhibition of human recombinant COX1 assessed as reduction in PGF2alpha formation using arachidonic acid as substrate preincubated with enzyme for 10 mins followed by substrate addition for 30 secs and measured after 1 hr by microplate reader based enzyme immunoassay
Format: BAO_0000357
Organism: Homo sapiens
Target: Cyclooxygenase-1(ALA221)
Document: ALA4393660
Inhibition of human recombinant COX1 assessed as reduction in PGF2alpha formation using arachidonic acid as substrate preincubated with enzyme for 10 mins followed by substrate addition for 30 secs and measured after 1 hr by microplate reader based enzyme immunoassay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4394179
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 381.38 | 3.51 | 3.51 |
| 353.79 | 0.96 | 0.96 |
| 367.39 | 1.64 | 1.64 |
| 404.45 | 0.05 | 0.05 |
| 351.39 | 2.14 | 2.14 |
| 404.45 | 0.05 | 0.05 |
| 347.36 | 0.53 | 0.53 |
| 385.84 | 2.80 | 2.80 |
| 339.76 | 0.57 | 0.57 |
| 390.43 | -0.34 | -0.34 |
| 353.79 | 0.96 | 0.96 |
| 430.29 | 2.90 | 2.90 |
| 369.38 | 2.28 | 2.28 |
| 411.44 | 2.16 | 2.16 |
| 381.42 | 2.15 | 2.15 |