Basic Information
ID: ALA4394180
Type: Binding
Description: Inhibition of human recombinant COX-2 assessed as reduction in PGF2alpha formation using arachidonic acid as substrate preincubated with enzyme for 10 mins followed by substrate addition for 30 secs and measured after 1 hr by microplate reader based enzyme immunoassay
Format: BAO_0000357
Organism: Homo sapiens
Target: Cyclooxygenase-2(ALA230)
Document: ALA4393660
Inhibition of human recombinant COX-2 assessed as reduction in PGF2alpha formation using arachidonic acid as substrate preincubated with enzyme for 10 mins followed by substrate addition for 30 secs and measured after 1 hr by microplate reader based enzyme immunoassay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4394180
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 381.38 | 3.51 | 3.51 |
| 353.79 | 0.96 | 0.96 |
| 367.39 | 1.64 | 1.64 |
| 404.45 | 0.05 | 0.05 |
| 351.39 | 2.14 | 2.14 |
| 404.45 | 0.05 | 0.05 |
| 347.36 | 0.53 | 0.53 |
| 385.84 | 2.80 | 2.80 |
| 339.76 | 0.57 | 0.57 |
| 390.43 | -0.34 | -0.34 |
| 353.79 | 0.96 | 0.96 |
| 430.29 | 2.90 | 2.90 |
| 369.38 | 2.28 | 2.28 |
| 411.44 | 2.16 | 2.16 |
| 381.42 | 2.15 | 2.15 |