Basic Information
ID: ALA4394182
Type: Toxicity
Description: Toxicity in carrageenan-induced albino rat paw edema model assessed as Inhibition of cytosolic PGE2 synthase expression in plasma at 10 umol/kg, sc treated 1 hr prior to carrageenan challenge measured after 2 hrs by microplate reader based monoclonal sandwich ELISA assay
Format: BAO_0000218
Organism: Rattus norvegicus
Tissue: Plasma
Target: ADMET(ALA612558)
Document: ALA4393660
Toxicity in carrageenan-induced albino rat paw edema model assessed as Inhibition of cytosolic PGE2 synthase expression in plasma at 10 umol/kg, sc treated 1 hr prior to carrageenan challenge measured after 2 hrs by microplate reader based monoclonal sandwich ELISA assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4394182
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 381.38 | 3.51 | 3.51 |
| 404.45 | 0.05 | 0.05 |
| 347.36 | 0.53 | 0.53 |
| 339.76 | 0.57 | 0.57 |
| 369.38 | 2.28 | 2.28 |
| 381.42 | 2.15 | 2.15 |