Basic Information
ID: ALA4394193
Type: ADME
Description: Substrate activity at Staphylococcus saprophyticus nitroreductase expressed in Escherichia coli assessed as product formation after 10 mins in the presence of NADPH at 100 uM by HPLC analysis relative to control (0 to 5 mins at 20 % ACN, 15 to 22 min at 80% ACN, 27-32 AT 20% ACN)
Format: BAO_0000019
Organism: Staphylococcus saprophyticus
Target: Putative nitroreductase(ALA4523956)
Document: ALA4393661
Substrate activity at Staphylococcus saprophyticus nitroreductase expressed in Escherichia coli assessed as product formation after 10 mins in the presence of NADPH at 100 uM by HPLC analysis relative to control (0 to 5 mins at 20 % ACN, 15 to 22 min at 80% ACN, 27-32 AT 20% ACN): 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4394193
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 236.23 | 1.07 | 1.07 |
| 287.11 | 2.73 | 2.73 |
| 420.29 | 2.64 | 2.64 |
| 346.26 | 2.97 | 2.97 |
| 375.30 | 2.73 | 2.73 |
| 358.31 | 1.66 | 1.66 |
| 234.25 | 2.22 | 2.22 |
| 412.40 | 2.97 | 2.97 |
| 259.06 | 2.32 | 2.32 |
| 412.40 | 2.97 | 2.97 |