Basic Information
ID: ALA4394211
Type: ADME
Description: Substrate activity at Staphylococcus saprophyticus nitroreductase expressed in Escherichia coli assessed as half life in the presence of NADPH at 100 uM by HPLC analysis (0 to 5 mins at 20% ACN, 25 to 35 min at 80% ACN, 40 to 45 min at 20% ACN)
Format: BAO_0000019
Organism: Staphylococcus saprophyticus
Target: Putative nitroreductase(ALA4523956)
Document: ALA4393661
Substrate activity at Staphylococcus saprophyticus nitroreductase expressed in Escherichia coli assessed as half life in the presence of NADPH at 100 uM by HPLC analysis (0 to 5 mins at 20% ACN, 25 to 35 min at 80% ACN, 40 to 45 min at 20% ACN): 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4394211
T1/2
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 384.35 | 2.10 | 2.10 |
| 406.35 | 4.01 | 4.01 |
| 420.29 | 2.64 | 2.64 |
| 346.26 | 2.97 | 2.97 |
| 412.40 | 2.97 | 2.97 |
| 358.31 | 1.66 | 1.66 |
| 234.25 | 2.22 | 2.22 |
| 412.40 | 2.97 | 2.97 |
| 412.40 | 2.97 | 2.97 |