Prodrug conversion assessed Staphylococcus saprophyticus nitroreductase expressed in Escherichia coli-mediated N,N'-(cyclohexane-1,4-diyl)bis(4-aminob...

Basic Information

ID: ALA4394213

Type: ADME

Description: Prodrug conversion assessed Staphylococcus saprophyticus nitroreductase expressed in Escherichia coli-mediated N,N'-(cyclohexane-1,4-diyl)bis(4-aminobenzamide) formation by measuring retention time at 100 uM incubated for 15 mins in presence of FDH cofactor regeneration system by HPLC analysis

Format: BAO_0000019

Organism: Staphylococcus saprophyticus

Target:  Putative nitroreductase(ALA4523956)

Document:  ALA4393661

Prodrug conversion assessed Staphylococcus saprophyticus nitroreductase expressed in Escherichia coli-mediated N,N'-(cyclohexane-1,4-diyl)bis(4-aminobenzamide) formation by measuring retention time at 100 uM incubated for 15 mins in presence of FDH cofactor regeneration system by HPLC analysis: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
412.402.972.97