Prodrug conversion assessed Staphylococcus saprophyticus nitroreductase expressed in Escherichia coli-mediated (4-aminophenyl)(piperidin-1-yl)methanon...

Basic Information

ID: ALA4394221

Type: ADME

Description: Prodrug conversion assessed Staphylococcus saprophyticus nitroreductase expressed in Escherichia coli-mediated (4-aminophenyl)(piperidin-1-yl)methanone metabolite formation by measuring retention time in presence of FDH cofactor regeneration system at 100 uM by HPLC analysis

Format: BAO_0000019

Organism: Staphylococcus saprophyticus

Target:  Putative nitroreductase(ALA4523956)

Document:  ALA4393661

Prodrug conversion assessed Staphylococcus saprophyticus nitroreductase expressed in Escherichia coli-mediated (4-aminophenyl)(piperidin-1-yl)methanone metabolite formation by measuring retention time in presence of FDH cofactor regeneration system at 100 uM by HPLC analysis: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
220.272.112.11
234.252.222.22