Prodrug conversion assessed Staphylococcus saprophyticus nitroreductase expressed in Escherichia coli-mediated PP (4-(hydroxyamino)phenyl)(piperidin-1...

Basic Information

ID: ALA4394224

Type: ADME

Description: Prodrug conversion assessed Staphylococcus saprophyticus nitroreductase expressed in Escherichia coli-mediated PP (4-(hydroxyamino)phenyl)(piperidin-1-yl)methanone metabolite formation by measuring retention time of metabolite at 100 uM incubated for 15 mins by HPLC analysis

Format: BAO_0000019

Organism: Staphylococcus saprophyticus

Target:  Putative nitroreductase(ALA4523956)

Document:  ALA4393661

Prodrug conversion assessed Staphylococcus saprophyticus nitroreductase expressed in Escherichia coli-mediated PP (4-(hydroxyamino)phenyl)(piperidin-1-yl)methanone metabolite formation by measuring retention time of metabolite at 100 uM incubated for 15 mins by HPLC analysis: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
236.231.071.07
220.272.112.11
234.252.222.22