ID: ALA4394235
Type: ADME
Description: Substrate activity at Staphylococcus saprophyticus nitroreductase expressed in Escherichia coli assessed as product formation after 10 mins in the presence of NADPH at 150 uM by HPLC analysis relative to control (0 to 5 mins at 20% ACN, 25 to 35 min at 80% ACN, 40 to 45 min at 20% ACN)
Format: BAO_0000019
Organism: Staphylococcus saprophyticus
Target: Putative nitroreductase(ALA4523956)
Document: ALA4393661
Substrate activity at Staphylococcus saprophyticus nitroreductase expressed in Escherichia coli assessed as product formation after 10 mins in the presence of NADPH at 150 uM by HPLC analysis relative to control (0 to 5 mins at 20% ACN, 25 to 35 min at 80% ACN, 40 to 45 min at 20% ACN): 1
Bioactivity
Activity Types for Assay ALA4394235
Drug metabolism
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
253.21 | 1.88 | 1.88 |