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Antagonist activity at Smo receptor in mouse NIH/3T3 cells harboring GRE-Luc assessed as inhibition of SAG-induced Hh signaling pathway preincubated w...

Basic Information

ID: ALA4394252

Type: Binding

Description: Antagonist activity at Smo receptor in mouse NIH/3T3 cells harboring GRE-Luc assessed as inhibition of SAG-induced Hh signaling pathway preincubated with cells followed by SAG addition measured after 48 hrs by luciferase reporter gene assay

Format: BAO_0000219

Organism: Mus musculus

Target:  Smoothened homolog(ALA6080)

Document:  ALA4393662

Antagonist activity at Smo receptor in mouse NIH/3T3 cells harboring GRE-Luc assessed as inhibition of SAG-induced Hh signaling pathway preincubated with cells followed by SAG addition measured after 48 hrs by luciferase reporter gene assay: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
421.314.714.71
492.695.165.16
493.684.124.12
494.673.953.95
494.673.953.95
495.653.923.92
495.663.353.35
489.613.603.60
410.552.862.86
402.573.253.25
489.613.603.60
495.663.353.35
508.704.174.17
495.663.353.35
480.643.643.64
504.705.435.43
489.613.603.60
489.613.603.60
493.684.564.56
388.542.852.85
494.673.953.95
418.572.692.69
494.673.953.95
404.542.132.13
374.512.642.64
468.483.843.84
488.624.204.20
480.643.643.64