Basic Information
ID: ALA4394252
Type: Binding
Description: Antagonist activity at Smo receptor in mouse NIH/3T3 cells harboring GRE-Luc assessed as inhibition of SAG-induced Hh signaling pathway preincubated with cells followed by SAG addition measured after 48 hrs by luciferase reporter gene assay
Organism: Mus musculus
Activity Charts
Bioactivity
Activity Types for Assay ALA4394252
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 421.31 | 4.71 | 4.71 |
| 492.69 | 5.16 | 5.16 |
| 493.68 | 4.12 | 4.12 |
| 494.67 | 3.95 | 3.95 |
| 494.67 | 3.95 | 3.95 |
| 495.65 | 3.92 | 3.92 |
| 495.66 | 3.35 | 3.35 |
| 489.61 | 3.60 | 3.60 |
| 410.55 | 2.86 | 2.86 |
| 402.57 | 3.25 | 3.25 |
| 489.61 | 3.60 | 3.60 |
| 495.66 | 3.35 | 3.35 |
| 508.70 | 4.17 | 4.17 |
| 495.66 | 3.35 | 3.35 |
| 480.64 | 3.64 | 3.64 |
| 504.70 | 5.43 | 5.43 |
| 489.61 | 3.60 | 3.60 |
| 489.61 | 3.60 | 3.60 |
| 493.68 | 4.56 | 4.56 |
| 388.54 | 2.85 | 2.85 |
| 494.67 | 3.95 | 3.95 |
| 418.57 | 2.69 | 2.69 |
| 494.67 | 3.95 | 3.95 |
| 404.54 | 2.13 | 2.13 |
| 374.51 | 2.64 | 2.64 |
| 468.48 | 3.84 | 3.84 |
| 488.62 | 4.20 | 4.20 |
| 480.64 | 3.64 | 3.64 |