Basic Information
ID: ALA4394392
Type: Binding
Description: Inhibition of HCV NS5B RNA-dependent RNA polymerase activity assessed as reduction in radiolabeled-UTP incorporation into RNA using cIRES template measured after 2 hrs by microscintillation counting method
Organism: Hepatitis C virus
Activity Charts
Bioactivity
Activity Types for Assay ALA4394392
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 520.58 | -0.96 | -0.96 |
| 526.15 | -2.20 | -2.20 |
| 516.16 | -1.81 | -1.81 |
| 508.16 | -2.50 | -2.50 |
| 510.15 | -1.52 | -1.52 |
| 518.15 | -0.84 | -0.84 |
| 528.14 | -1.22 | -1.22 |
| 528.17 | -1.65 | -1.65 |
| 534.15 | -1.86 | -1.86 |
| 530.18 | -1.42 | -1.42 |
| 534.60 | -0.57 | -0.57 |
| 538.57 | -0.66 | -0.66 |
| 516.16 | -2.16 | -2.16 |