Basic Information
ID: ALA4394394
Type: ADME
Description: Inhibition of human DNA polymerase-alpha assessed as reduction in [3H]dTTP incorporation in to activated calf thymus DNA substrate at 100 uM by scintillation counting method relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4394394
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 500.16 | -1.13 | -1.13 |
| 498.17 | -2.11 | -2.11 |
| 516.61 | -0.86 | -0.86 |
| 520.58 | -0.96 | -0.96 |
| 516.16 | -1.81 | -1.81 |
| 518.15 | -0.84 | -0.84 |
| 534.60 | -0.57 | -0.57 |
| 538.57 | -0.66 | -0.66 |