Basic Information
ID: ALA4394432
Type: Binding
Description: Binding affinity to human N-terminal His6-tagged RORgamma (262 to 507 residues) expressed in Escherichia coli BL21 (DE3) assessed as change in melting temperature at 200 uM by SYPRO orange-dye based fluorescence assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4394432
Delta Tm
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 563.49 | 5.78 | 5.78 |
| 565.46 | 5.53 | 5.53 |
| 451.38 | 6.32 | 6.32 |
| 437.36 | 5.93 | 5.93 |
| 550.45 | 4.85 | 4.85 |
| 552.42 | 5.66 | 5.66 |
| 565.46 | 5.53 | 5.53 |
| 585.52 | 5.15 | 5.15 |
| 481.36 | 5.09 | 5.09 |
| 552.42 | 5.66 | 5.66 |
| 564.48 | 5.11 | 5.11 |
| 486.39 | 5.57 | 5.57 |
| 465.41 | 6.71 | 6.71 |
| 516.37 | 5.89 | 5.89 |
| 467.34 | 4.70 | 4.70 |
| 465.37 | 5.50 | 5.50 |
| 552.42 | 5.66 | 5.66 |
| 516.37 | 5.89 | 5.89 |
| 485.40 | 6.38 | 6.38 |
| 505.47 | 7.49 | 7.49 |
| 486.39 | 5.57 | 5.57 |
| 549.46 | 5.39 | 5.39 |
| 565.46 | 5.53 | 5.53 |
| 477.30 | 6.09 | 6.09 |
| 551.44 | 5.45 | 5.45 |
| 532.44 | 5.62 | 5.62 |