Basic Information
ID: ALA4394441
Type: Binding
Description: Inverse agonist activity at human N-terminal His6-tagged RORgamma (262 to 507 residues) expressed in Escherichia coli BL21 (DE3) assessed as inhibition of biotinylated co-activator SRC1-4 peptide recruitment by alphascreen assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4394441
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 563.49 | 5.78 | 5.78 |
| 565.46 | 5.53 | 5.53 |
| 465.41 | 6.71 | 6.71 |
| 516.37 | 5.89 | 5.89 |
| 549.46 | 5.39 | 5.39 |