Basic Information
ID: ALA4394508
Type: Binding
Description: Inhibition of EGFR in human A431 cells assessed as reduction in EGF-stimulated EGFR autophosphorylation preincuabted for 90 mins followed by EGF-stimulation by sandwich-ELISA
Format: BAO_0000219
Organism: Homo sapiens
Target: Epidermal growth factor receptor erbB1(ALA203)
Document: ALA4393671
Inhibition of EGFR in human A431 cells assessed as reduction in EGF-stimulated EGFR autophosphorylation preincuabted for 90 mins followed by EGF-stimulation by sandwich-ELISA: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4394508
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 393.44 | 3.41 | 3.41 |
| 581.07 | 6.14 | 6.14 |
| 360.21 | 4.15 | 4.15 |
| 446.91 | 4.28 | 4.28 |
| 305.34 | 3.37 | 3.37 |
| 395.42 | 3.89 | 3.89 |
| 370.41 | 4.02 | 4.02 |
| 371.39 | 3.42 | 3.42 |
| 359.22 | 4.76 | 4.76 |
| 384.23 | 4.63 | 4.63 |
| 542.04 | 3.94 | 3.94 |
| 378.35 | 5.02 | 5.02 |
| 467.93 | 5.10 | 5.10 |
| 392.46 | 4.01 | 4.01 |
| 304.35 | 3.98 | 3.98 |
| 469.95 | 5.16 | 5.16 |
| 473.94 | 3.76 | 3.76 |
| 491.39 | 5.79 | 5.79 |
| 329.36 | 3.85 | 3.85 |
| 389.25 | 4.77 | 4.77 |
| 379.34 | 4.42 | 4.42 |
| 438.89 | 6.37 | 6.37 |
| 392.38 | 5.05 | 5.05 |
| 439.87 | 5.76 | 5.76 |
| 459.50 | 3.45 | 3.45 |
| 458.57 | 3.93 | 3.93 |
| 392.38 | 5.33 | 5.33 |