Basic Information
ID: ALA4394697
Type: Binding
Description: Inhibition of recombinant human N-terminal GST-tagged CHK1 (M1 to T476 residues) expressed in baculovirus infected insect cells using biotin-labelled STK substrate-1 as substrate incubated for 60 mins by HTRF assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4394697
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 436.31 | 2.87 | 2.87 |
| 365.40 | 2.22 | 2.22 |
| 393.46 | 1.87 | 1.87 |
| 372.43 | 3.28 | 3.28 |
| 391.44 | 2.92 | 2.92 |
| 405.47 | 2.06 | 2.06 |
| 407.48 | 2.26 | 2.26 |
| 431.50 | 3.33 | 3.33 |
| 405.47 | 2.06 | 2.06 |
| 405.47 | 2.06 | 2.06 |
| 373.42 | 2.68 | 2.68 |
| 465.54 | 3.17 | 3.17 |
| 372.43 | 3.28 | 3.28 |
| 402.46 | 3.29 | 3.29 |
| 405.47 | 2.06 | 2.06 |
| 419.46 | 3.47 | 3.47 |
| 378.46 | 3.35 | 3.35 |
| 390.42 | 3.42 | 3.42 |
| 406.45 | 2.03 | 2.03 |
| 419.49 | 2.40 | 2.40 |
| 373.42 | 2.68 | 2.68 |
| 419.46 | 3.47 | 3.47 |
| 407.50 | 3.39 | 3.39 |
| 402.46 | 2.72 | 2.72 |
| 405.47 | 2.06 | 2.06 |
| 362.39 | 2.88 | 2.88 |
| 273.30 | 3.15 | 3.15 |
| 390.42 | 3.42 | 3.42 |
| 419.46 | 3.47 | 3.47 |
| 402.46 | 2.72 | 2.72 |
| 419.49 | 2.31 | 2.31 |
| 461.53 | 3.34 | 3.34 |
| 376.42 | 2.02 | 2.02 |
| 391.44 | 1.67 | 1.67 |
| 431.50 | 3.33 | 3.33 |
| 402.46 | 3.29 | 3.29 |
| 465.52 | 2.06 | 2.06 |
| 422.52 | 3.09 | 3.09 |
| 401.47 | 3.33 | 3.33 |
| 407.48 | 2.26 | 2.26 |