Basic Information
ID: ALA4394736
Type: Binding
Description: Inhibition of 2-((1E,3E,5E)-5-(1-(6-((((3S,5S)-1-((1-carbamoyl-1H-indol-3-yl)carbamoyl)-5-((3-chloro-2-fluorobenzyl)carbamoyl)-3-fluoropyrrolidin-3-yl)methyl)amino)-6-oxohexyl)-3,3-dimethyl-5-sulfoindolin-2-ylidene)penta-1,3-dien-1-yl)-1-ethyl-3,3-dimethyl-5-sulfo-3H-indol-1-ium binding to biotin-labeled recombinant human FD expressed in Escherichia coli measured after 2 hrs by TR-FRET assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA4394736
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 356.47 | 4.62 | 4.62 |
| 407.47 | 3.04 | 3.04 |
| 437.52 | 3.03 | 3.03 |
| 434.54 | 4.37 | 4.37 |
| 346.43 | 4.05 | 4.05 |
| 347.41 | 4.02 | 4.02 |
| 347.41 | 4.02 | 4.02 |
| 374.44 | 3.78 | 3.78 |
| 360.41 | 3.69 | 3.69 |
| 421.49 | 3.70 | 3.70 |
| 361.44 | 4.58 | 4.58 |
| 456.34 | 4.31 | 4.31 |
| 384.44 | 3.17 | 3.17 |
| 391.47 | 3.94 | 3.94 |
| 377.44 | 3.55 | 3.55 |
| 361.40 | 3.09 | 3.09 |
| 435.52 | 3.78 | 3.78 |