Assay Report Card

Basic Information

ID: ALA4394763

Type: Functional

Description: Suppression of intravitreal injection-activated alternative complementation pathway in human FD knock-in C57BL/6 mouse model of local ocular injury assessed as reduction in ocular Ba level at 10 mg/kg, po treated via gavage 2 hrs prior to intravitreal injection and measured after 4 hrs by Western blot analysis relative to control

Organism: Mus musculus

Strain: C57BL/6

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
377.443.553.55