Basic Information
ID: ALA4394937
Type: Binding
Description: Inhibition of human recombinant His-tagged HDAC1 (482 residues) expressed in baculovirus infected insect cells using FLUOR DE LYS SIRT1 as substrate incubated for 10 mins followed by substrate addition and measured after 30 mins by fluorescence method
Format: BAO_0000219
Organism: Homo sapiens
Target: Histone deacetylase 1(ALA325)
Document: ALA4393680
Inhibition of human recombinant His-tagged HDAC1 (482 residues) expressed in baculovirus infected insect cells using FLUOR DE LYS SIRT1 as substrate incubated for 10 mins followed by substrate addition and measured after 30 mins by fluorescence method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4394937
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 376.42 | 3.34 | 3.34 |
| 269.30 | 2.48 | 2.48 |
| 390.42 | 3.38 | 3.38 |
| 446.53 | 4.07 | 4.07 |
| 543.05 | 6.17 | 6.17 |
| 486.60 | 4.95 | 4.95 |
| 495.40 | 4.82 | 4.82 |