Basic Information
ID: ALA4395035
Type: Binding
Description: Inhibition of human recombinant N-terminal His6-tagged 15-LOX1 expressed in Escherichia coli BL21(DE3) using linoleic acid as substrate preincubated for 8 mins followed by substrate addition by UV absorption analysis
Format: BAO_0000019
Organism: Homo sapiens
Target: Arachidonate 15-lipoxygenase(ALA2903)
Document: ALA4393683
Inhibition of human recombinant N-terminal His6-tagged 15-LOX1 expressed in Escherichia coli BL21(DE3) using linoleic acid as substrate preincubated for 8 mins followed by substrate addition by UV absorption analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4395035
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 443.85 | 3.47 | 3.47 |
| 434.28 | 4.18 | 4.18 |
| 449.89 | 4.68 | 4.68 |
| 496.78 | 5.61 | 5.61 |
| 434.28 | 4.18 | 4.18 |
| 349.82 | 3.64 | 3.64 |
| 520.03 | 5.61 | 5.61 |
| 468.72 | 4.83 | 4.83 |
| 375.86 | 4.03 | 4.03 |
| 476.96 | 4.10 | 4.10 |
| 384.82 | 3.09 | 3.09 |
| 455.93 | 4.12 | 4.12 |
| 512.99 | 4.58 | 4.58 |
| 363.85 | 3.88 | 3.88 |
| 443.89 | 3.71 | 3.71 |
| 399.83 | 3.40 | 3.40 |
| 389.86 | 3.75 | 3.75 |
| 383.84 | 3.69 | 3.69 |
| 444.83 | 3.44 | 3.44 |
| 397.86 | 4.08 | 4.08 |
| 399.83 | 3.53 | 3.53 |