Basic Information
ID: ALA4395044
Type: Binding
Description: Inhibition of human recombinant N-terminal His6-tagged 15-LOX1 expressed in Escherichia coli BL21(DE3) assessed as residual enzyme activity at 0.5 uM using linoleic acid as substrate preincubated for 8 mins followed by substrate addition by UV absorption analysis relative to control
Format: BAO_0000019
Organism: Homo sapiens
Target: Arachidonate 15-lipoxygenase(ALA2903)
Document: ALA4393683
Inhibition of human recombinant N-terminal His6-tagged 15-LOX1 expressed in Escherichia coli BL21(DE3) assessed as residual enzyme activity at 0.5 uM using linoleic acid as substrate preincubated for 8 mins followed by substrate addition by UV absorption analysis relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4395044
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 251.67 | 2.81 | 2.81 |
| 363.80 | 2.48 | 2.48 |
| 443.85 | 3.47 | 3.47 |
| 434.28 | 4.18 | 4.18 |
| 449.89 | 4.68 | 4.68 |
| 390.83 | 2.07 | 2.07 |
| 496.78 | 5.61 | 5.61 |
| 361.83 | 3.64 | 3.64 |
| 379.80 | 1.86 | 1.86 |
| 375.73 | 3.40 | 3.40 |
| 349.82 | 3.49 | 3.49 |
| 347.80 | 3.10 | 3.10 |
| 333.78 | 2.86 | 2.86 |
| 353.83 | 2.81 | 2.81 |
| 349.82 | 3.64 | 3.64 |
| 385.83 | 1.49 | 1.49 |
| 520.03 | 5.61 | 5.61 |
| 347.80 | 3.25 | 3.25 |
| 349.82 | 3.49 | 3.49 |
| 375.86 | 4.03 | 4.03 |
| 337.76 | 2.09 | 2.09 |
| 476.96 | 4.10 | 4.10 |
| 411.87 | 1.88 | 1.88 |
| 384.82 | 3.09 | 3.09 |
| 364.83 | 2.40 | 2.40 |
| 425.89 | 2.27 | 2.27 |
| 429.93 | 4.70 | 4.70 |
| 512.99 | 4.58 | 4.58 |
| 363.85 | 3.88 | 3.88 |
| 350.81 | 2.01 | 2.01 |
| 363.80 | 2.63 | 2.63 |
| 363.85 | 3.88 | 3.88 |
| 365.82 | 2.87 | 2.87 |
| 335.79 | 3.10 | 3.10 |
| 399.83 | 3.40 | 3.40 |
| 389.86 | 3.75 | 3.75 |
| 383.84 | 3.69 | 3.69 |
| 444.83 | 3.44 | 3.44 |
| 397.86 | 4.08 | 4.08 |
| 418.88 | 2.85 | 2.85 |
| 399.83 | 3.53 | 3.53 |