Basic Information
ID: ALA4395090
Type: Binding
Description: Inhibition of recombinant His-tagged human PDE4B expressed in Sf9 cells using cAMP as substrate preincubated with enzyme for 15 mins followed by substrate addition and incubated for 1 hr by PDELight HTS cAMP phosphodiesterase Kit based luminometry
Organism: Homo sapiens
Cell type: Sf9
Activity Charts
Bioactivity
Activity Types for Assay ALA4395090
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 275.35 | 2.62 | 2.62 |
| 319.80 | 5.09 | 5.09 |
| 365.86 | 5.88 | 5.88 |
| 351.84 | 5.49 | 5.49 |
| 349.82 | 5.10 | 5.10 |
| 435.91 | 5.68 | 5.68 |
| 449.94 | 6.07 | 6.07 |
| 400.71 | 6.25 | 6.25 |
| 363.80 | 4.62 | 4.62 |
| 395.85 | 4.48 | 4.48 |
| 289.34 | 3.77 | 3.77 |