Basic Information
ID: ALA4395365
Type: Functional
Description: Antitrypanosomal activity against bloodstream form of Trypanosoma brucei gambiense Feo reduction in parasite growth after 72 hrs by resazurin dye based fluorescence assay
Format: BAO_0000218
Organism: Trypanosoma brucei gambiense
Strain: Feo
Target: Trypanosoma brucei gambiense(ALA613768)
Document: ALA4393692
Antitrypanosomal activity against bloodstream form of Trypanosoma brucei gambiense Feo reduction in parasite growth after 72 hrs by resazurin dye based fluorescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA4395365
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 340.43 | 2.88 | 2.88 |
| 287.30 | 0.64 | 0.64 |
| 229.31 | 3.02 | 3.02 |
| 475.56 | 4.92 | 4.92 |
| 382.88 | 4.43 | 4.43 |
| 443.51 | 3.26 | 3.26 |
| 422.54 | 4.05 | 4.05 |
| 507.84 | 7.82 | 7.82 |
| 466.62 | 4.76 | 4.76 |
| 396.90 | 4.82 | 4.82 |
| 452.54 | 5.03 | 5.03 |
| 384.49 | 2.96 | 2.96 |
| 576.73 | 5.71 | 5.71 |
| 442.60 | 4.07 | 4.07 |
| 547.04 | 5.99 | 5.99 |
| 522.66 | 6.18 | 6.18 |
| 477.41 | 4.11 | 4.11 |
| 474.59 | 3.05 | 3.05 |
| 488.62 | 3.44 | 3.44 |
| 449.49 | 5.13 | 5.13 |
| 463.39 | 3.72 | 3.72 |
| 576.59 | 6.81 | 6.81 |
| 476.59 | 4.58 | 4.58 |
| 462.96 | 5.94 | 5.94 |
| 485.55 | 3.74 | 3.74 |
| 462.56 | 4.20 | 4.20 |
| 474.97 | 6.05 | 6.05 |
| 368.85 | 4.04 | 4.04 |
| 441.35 | 4.93 | 4.93 |
| 467.54 | 3.95 | 3.95 |
| 554.46 | 5.68 | 5.68 |
| 440.55 | 3.83 | 3.83 |
| 593.65 | 4.43 | 4.43 |
| 627.55 | 5.28 | 5.28 |
| 374.52 | 2.90 | 2.90 |
| 611.55 | 5.76 | 5.76 |
| 484.63 | 4.55 | 4.55 |
| 592.73 | 5.23 | 5.23 |
| 541.59 | 5.72 | 5.72 |
| 518.40 | 7.08 | 7.08 |
| 476.99 | 6.33 | 6.33 |
| 428.57 | 3.68 | 3.68 |
| 439.50 | 6.31 | 6.31 |
| 569.51 | 5.74 | 5.74 |
| 577.65 | 4.91 | 4.91 |
| 457.35 | 3.90 | 3.90 |
| 519.45 | 4.59 | 4.59 |
| 500.63 | 3.61 | 3.61 |
| 499.55 | 5.70 | 5.70 |
| 370.46 | 2.57 | 2.57 |
| 489.00 | 6.44 | 6.44 |
| 472.58 | 3.13 | 3.13 |
| 680.45 | 7.70 | 7.70 |
| 555.48 | 5.35 | 5.35 |
| 257.32 | 2.83 | 2.83 |
| 501.44 | 4.81 | 4.81 |
| 273.39 | 3.74 | 3.74 |
| 420.49 | 3.71 | 3.71 |
| 319.41 | 3.11 | 3.11 |
| 414.54 | 3.29 | 3.29 |
| 427.33 | 4.54 | 4.54 |
| 532.65 | 5.00 | 5.00 |
| 301.40 | 3.55 | 3.55 |
| 535.03 | 5.87 | 5.87 |
| 460.95 | 5.66 | 5.66 |
| 646.55 | 6.85 | 6.85 |
| 412.90 | 3.79 | 3.79 |
| 454.94 | 4.36 | 4.36 |
| 330.44 | 2.19 | 2.19 |
| 520.56 | 4.83 | 4.83 |
| 548.65 | 4.52 | 4.52 |
| 375.44 | 2.10 | 2.10 |
| 409.34 | 2.95 | 2.95 |
| 407.46 | 4.07 | 4.07 |
| 362.46 | 4.17 | 4.17 |
| 534.69 | 5.69 | 5.69 |
| 501.55 | 2.80 | 2.80 |
| 334.40 | 3.39 | 3.39 |
| 535.45 | 3.66 | 3.66 |
| 492.99 | 5.30 | 5.30 |
| 490.61 | 4.97 | 4.97 |
| 499.39 | 4.47 | 4.47 |
| 456.55 | 2.89 | 2.89 |
| 393.43 | 3.68 | 3.68 |
| 554.46 | 5.68 | 5.68 |
| 520.67 | 5.30 | 5.30 |
| 348.43 | 3.78 | 3.78 |
| 646.55 | 6.85 | 6.85 |
| 612.65 | 6.00 | 6.00 |
| 506.64 | 4.91 | 4.91 |
| 398.52 | 3.35 | 3.35 |
| 438.94 | 5.88 | 5.88 |
| 448.94 | 5.55 | 5.55 |