Antimycobacterial activity against Mycobacterium tuberculosis H37Rv SRMV2.6 harboring GuaB2 Tyr487Cys mutant assessed as reduction in bacterial cell g...

Basic Information

ID: ALA4395372

Type: Functional

Description: Antimycobacterial activity against Mycobacterium tuberculosis H37Rv SRMV2.6 harboring GuaB2 Tyr487Cys mutant assessed as reduction in bacterial cell growth incubated for 3 to 4 weeks by alamar blue fluorescence based broth microdilution assay

Format: BAO_0000218

Organism: Mycobacterium tuberculosis

Strain: H37Rv SRMV2.6

Target: Mycobacterium tuberculosis(ALA360)

Document: ALA4393693

Antimycobacterial activity against Mycobacterium tuberculosis H37Rv SRMV2.6 harboring GuaB2 Tyr487Cys mutant assessed as reduction in bacterial cell growth incubated for 3 to 4 weeks by alamar blue fluorescence based broth microdilution assay: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA4395372

MIC90

Total(49)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
386.52	3.25	3.25
361.47	2.21	2.21
475.91	3.33	3.33
406.47	2.25	2.25
448.91	3.57	3.57
381.46	2.38	2.38
401.53	3.04	3.04
425.51	2.32	2.32
386.52	3.25	3.25
319.39	1.04	1.04
471.45	2.20	2.20
430.92	3.43	3.43
401.53	3.08	3.08
426.45	2.29	2.29
454.51	2.89	2.89
401.53	3.04	3.04
411.48	2.02	2.02
411.48	2.88	2.88
401.53	2.96	2.96
421.48	2.64	2.64
387.51	2.65	2.65
445.41	1.76	1.76
406.47	2.25	2.25
410.50	2.45	2.45
455.54	2.33	2.33
444.94	3.74	3.74
456.55	2.67	2.67
465.36	4.08	4.08
440.48	2.50	2.50
401.53	3.04	3.04
413.47	2.45	2.45
455.50	2.99	2.99
464.47	3.79	3.79
333.41	1.43	1.43
444.94	3.74	3.74
454.51	2.94	2.94
401.53	2.89	2.89
440.53	2.46	2.46
498.91	4.45	4.45
401.53	3.04	3.04
420.49	2.18	2.18
401.53	3.08	3.08
409.51	2.62	2.62
471.54	2.41	2.41
440.48	2.22	2.22
424.53	2.76	2.76
361.47	2.11	2.11
454.51	2.89	2.89
459.57	2.39	2.39