Assay Report Card

Basic Information

ID: ALA4395393

Type: Binding

Description: Binding affinity to G-quadruplex G1 DNA (unknown origin) assessed as melting temperature at compound to DNA ratio of 4:1 in presence of 150 mM Na+ by circular dichroism thermal denaturation analysis (Rvb = 57.4 degC)

Organism: Not specified

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
429.343.683.68
525.523.813.81
340.884.204.20
539.544.204.20
441.003.073.07
471.032.692.69
513.111.851.85
426.972.682.68
569.573.833.83
559.132.722.72
583.604.224.22
569.223.413.41
498.103.043.04
483.084.244.24