Basic Information
ID: ALA4395491
Type: Binding
Description: Inhibition of GCase in human SH-SY5Y cells using MUG-Gluc as fluorogenic substrate preincubated for 30 mins followed by substrate addition and measured after 2 hrs in presence of conduritol B epoxide by fluorescence based assay
Organism: Homo sapiens
Cell type: SH-SY5Y
Activity Charts
Bioactivity
Activity Types for Assay ALA4395491
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 219.28 | -1.45 | -1.45 |
| 219.28 | -1.45 | -1.45 |
| 289.42 | 0.50 | 0.50 |
| 289.42 | 0.50 | 0.50 |
| 397.56 | 1.15 | 1.15 |
| 333.47 | 0.51 | 0.51 |
| 375.55 | 1.68 | 1.68 |
| 219.28 | -1.45 | -1.45 |
| 397.56 | 1.15 | 1.15 |
| 333.47 | 0.51 | 0.51 |
| 333.47 | 0.51 | 0.51 |
| 375.55 | 1.68 | 1.68 |
| 289.42 | 0.50 | 0.50 |
| 397.56 | 1.15 | 1.15 |
| 375.55 | 1.68 | 1.68 |